Thus, the concept is emerging that these tissues have, to a great degree, the same set of biosynthetic enzymes, but differ in the relative activities or amounts of different individual enzymes. Present developments of enzyme chemistry point toward a qualitative similarity of the biosynthetic systems in all tissues forming steroid hormones ( Samuels 1958).
The embryological origin of these tissues from adjacent portions of the dorsal mesentery provided a plausible background for similarities ( Poll 1900, Politzer 1937, Gruenwald 1942).
The production of sex hormones by congenital hyperplasias or malignancies of the adrenal cortex has long been recognized as suggestive of a biochemical relationship between the adrenal cortex and the gonads.
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